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Ah, the sweet agony of waiting for the next season of a show that has you hooked. It’s like you’re in a relationship with a TV series—one minute, you’re on top of the world, and the next, you’re left with nothing but cliffhangers and ‘to be continued’… Well, let’s face it, there’s nothing quite like the buzz that fills the air when a beloved anime confirms its return.The Apothecary Diarieshas given us exactly that!

Maomao explaining poisons in The Apothecary Diaries.

As Season 1 wrapped up in March 2024, fans were left reeling, their brains buzzing with questions and theories. Frustrating yet thrilling at the same time, right? But hey, isn’t that how the saying goes? Good things come to those who wait. Indeed, get ready to reap the rewards because Season 2 is on its way, and it’s gearing up to shake things up and flip everything you thought you knew upside down.

And, what’s next for Maomao, the insightful yet mysterious protagonist, and the intricately designed world ofThe Apothecary Diaries? Let’s dive into what we know about the upcoming season, from the release date to the cast and, of course, all the juicy plot details.

Jinshi kisses Maomao’s neck in The Apothecary Diaries.

A look back at season 1 ofThe Apothecary Diaries

Before we dive into the juicy details of Season 2, let’s take a quick look at what made the first season ofThe Apothecary Diariessuch a standout. If you haven’t watched it yet, you’re missing out on one of the most thrilling anime adaptations in recent years.

Based on the light novel series by Natsu Hyūga and illustrated by Touko Shino,The Apothecary Diariesis a mix of mystery, medical drama, and palace intrigue. The show introduced us to Maomao, a sharp-witted young woman with a knack for medicine, who finds herself sold into service at the emperor’s palace.

Lakan’s Impossible Demand for Blue Roses in The Apothecary Diaries Had a Hidden Meaning Fans Missed

Her knowledge of herbs and poisons quickly catches the eye of Jinshi, a high-ranking eunuch in the palace, who sees potential in her. Maomao’s journey to solving medical mysteries, as well as navigating the treacherous world of palace politics, is a thrilling ride filled with twists and turns. As the season progresses, Maomao’s sharp observations unravel secrets that make her a target, but also a crucial player at the imperial court.

Lakan’s Impossible Demand for Blue Roses in The Apothecary Diaries Had a Hidden Meaning Fans Missed

With such a compelling premise, it’s no wonder that fans are eagerly awaiting what happens next. The first season laid the groundwork for a much larger story, and it’s clear that there’s much more to uncover. With mysteries still left unsolved and dangers lurking just ahead, the second season promises to be a rollercoaster of suspense and drama.

The cast of The Apothecary Diaries 2: Who’s coming back?

If you’re a fan of the show, you’ll be pleased to know that the main voice cast will be returning for Season 2 ofThe Apothecary Diaries.As we learned fromGame Rant, Aoi Yūki will reprise her role as Maomao, bringingher sharp intelligence and fierce determinationto life once again.

Takeo Ōtsuka is set to reprise his role as Jinshi, the enigmatic and handsome eunuch who has become a key figure in Maomao’s life. Katsuyuki Konishi will also return as Gaoshun, while other returning voice actors include Atsumi Tanezaki as Gyokuyō, Yui Ishikawa as Lihua, and Hina Kino as Lishu. The chemistry between these talented actors is undeniable, and their exceptional performances are bound to intensify the drama and suspense in Season 2.

Maomao on Lihua’s lap in The Apothecary Diaries.

Let’s know about the creative minds poweringThe Apothecary Diaries

Behind the success ofThe Apothecary Diarieslies the hard work and creative brilliance of many individuals whose combined efforts have brought the rich world of Maomao and the imperial palace to life.

At the helm of this second season is Norihiro Naganuma (via Games Rant), the director who has worked on some of the most beloved anime series likeThe Ancient Magus’ BrideandThe Girl Who Leapt Through Time.

Maomao at the garden party in The Apothecary Diaries.

Supporting him is Akinori Fudesaka as the assistant director. Fudesaka’s pedigree, with credits inTsuredure Children, andThe Lost Village, ensures the action sequences and emotional beats will hit just right. He’s no stranger to creating worlds that pull you in and refuse to let go.

When it comes to character design, we’re in trustworthy hands with Yukiko Nakatani. With a portfolio that includesDragon Ball Super: Broly,One Piece, andPandora Hearts, Nakatani’s designs will bring the characters ofThe Apothecary Diariesto life in ways that are both fresh and familiar. Expect to see some truly stunning character art that balances style with emotion.

The visual appeal extends far beyond character design, though. Misato Aida’s role as color designer promises to fill each scene with hues that pop. With previous work onFrom Up on Poppy HillandWhen Marnie Was There, Aida’s ability to set the tone through color is unparalleled, and it will undoubtedly heighten the emotional impact of every moment.

The Apothecary Diaries Perfectly Knows How to Hype Season 2 by Teasing THAT Scene in Its Trailer

In the world of anime, atmosphere is everything, and that’s where Katsumi Takao comes in. As the art director, his past work onWonder Beat SandPokémonensures that the environments and settings ofThe Apothecary Diarieswill be as tempting as the story itself.

Music is the heartbeat of any great story, andThe Apothecary Diariesis no exception. With Satoru Kousaki, Kevin Penkin, and Alisa Okehazama composing the music, fans can expect a soundtrack that is as unforgettable as the story itself.

It’s not just the creators behind the scenes who makeThe Apothecary Diariesseason two shine—it’s the animation studio that’s bringing the vision to life. The combined efforts ofTOHO Animation StudioandOLMare the perfect partnership. These studios are renowned for their work on series likeKaiju No. 8andSpy × Family, and together, they’re set to deliver a season ofThe Apothecary Diariesthat will be nothing short of a visual masterpiece.

So what’s the release date ofThe Apothecary Diaries?

In case you missed it,The Apothecary Diaries’sfirst season began airing in October 2023 and spans two cours, wrapping up with a season finale that dropped on August 19, 2025. And just when we thought we couldn’t get enough, thetrailerfor season two arrived, giving us a tantalizing taste of what’s to come. In less than a minute, it packs in enough action to make your head spin, hinting at even more twists and turns in Maomao’s journey that will keep us hooked for sure.

So, when can you expect to see the return ofThe Apothecary Diaries?  The hit anime, based on Natsu Hyūga’s light novel series, is back with its much-anticipated second season, set to drop its first episode on January 10th, 2025, onCrunchyroll.

【Official Trailer】The Apothecary Diaries Season 2Scheduled for June 30, 2025!The anime airs over 2 consecutive cours!✨More:https://t.co/pUsNR90qTypic.twitter.com/tg6Jw0y7fU

With season 2 just around the corner, fans are already playing detective on what’s next for Maomao. Will she continue to outwit her enemies, solving medical puzzles and uncovering hidden agendas? Or will new challenges and dangers arise that test her skills and determination? Well, she’s definitely geared up to face whatever curveballs come her way, ready to turn the tide in her favor once again.

So, circle January 10th, 2025 on your calendars, because the countdown is officially on! Trust us, the second season ofThe Apothecary Diarieswill be worth every minute of the wait.

The Apothecary Diariesis currently streaming on Crunchyroll.

Siddhika Prajapati

Senior Journalist & Content Head

Articles Published :3309

With over 3,300 articles carved into the digital walls of FandomWire, Siddhika Prajapati excels at creating, curating, and elevating engaging stories. She takes pride in giving these stories a home and, of course, she’s got a Google Knowledge Panel to prove it!Whether it’s reviewing the latest drop on Netflix, Amazon Prime, or Apple TV+, or analyzing the cultural echoes of a streaming hit on Paramount+ or Max, Siddhika is always writing three steps ahead of the discourse.

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The Apothecary Diaries